Update on the development of a novel dry cow therapy using a bismuth-based intramammary teat seal in combination with the bacteriocin lacticin 3147

Table 2 The effectiveness of teat seal plus lacticin (32,768 AU/4 g teat seal) in eliminating Staphylococcus aureus DPC5246 from artificially infected udder quarters of lactating cows compared with untreated controls. Shedding was evaluated 18 h after inoculation of S. aureus

Treatment	Inoculum (cfu per 0.1 ml)	Quarters inoculated (n)	Quarters shedding S. aureus
Untreated	1.7 × 10³	29	19 (66%)^a
Teat seal + lacticin		29	4 (14%)^b
Untreated	6.8 × 10³	20	16 (80%)
Teat seal + lacticin		20	11 (55%)

^a,b Values with different superscripts within an experiment are significant P <0.001.

ISSN: 2046-0481