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Table 1 Cardiorespiratory parameters (heart rate, respiratory rate, arterial oxyhaemoglobin saturation and end-tidal CO2), blood gas values and rectal temperatures of rabbits anaesthetised with sevoflurane (SEVO) and isoflurane (ISO).

From: Comparison of the arterial blood gas, arterial oxyhaemoglobin saturation and end-tidal carbon dioxide tension during sevoflurane or isoflurane anaesthesia in rabbits

   B I 15 30 45 60 75 90
HR (beats/min) ISO 218 ± 70 188 ± 43ab 200 ± 31ab 209 ± 25b 201 ± 14ab 196 ± 23ab 209 ± 31b 198 ± 39ab
  SEVO 234 ± 58 54 ± 27a 233 ± 35 244 ± 39 240 ± 42 255 ± 41a 260 ± 42a 266 ± 29a
RR (beats/min) SEVO 100 ± 30 38 ± 7ab 37 ± 8a 36 ± 5a 34 ± 5a 36 ± 11a 35 ± 9a 34 ± 9a
  ISO 78 ± 24 43 ± 13a 36 ± 12a 34 ± 10a 37 ± 10a 34 ± 10a 32 ± 7a 35 ± 5a
SpO2 (%) SEVO 91 ± 5 91 ± 4 91 ± 4 90 ± 4 94 ± 2 94 ± 2 92 ± 4 89 ± 6
  ISO 94 ± 3 94 ± 4 90 ± 4 91 ± 5 93 ± 4 93 ± 3 94 ± 4 94 ± 3
ETCO2 (mmHg) SEVO ND 32 ± 9 36 ± 6 37 ± 6 35 ± 7 36 ± 4 36 ± 6 37 ± 5
  ISO ND 28 ± 10 29 ± 8 30 ± 6 30 ± 5 33 ± 7 34 ± 7 32 ± 8
pH SEVO 7.40 ± 0.04 7.25 ± 0.11a 7.32 ± 0.06 7.39 ± 0.08 7.41 ± 0.04 7.38 ± 0.05 7.41 ± 0.05 7.39 ± 0.05
  ISO 7.38 ± 0.05 7.16 ± 0.09a 7.34 ± 0.08 7.40 ± 0.06 7.41 ± 0.04 7.41 ± 0.05 7.41 ± 0.05 7.42 ± 0.05
PaCO2 (mmHg) SEVO 30.5 ± 7.0 48.1 ± 11.5a 46.1 ± 6.9a 45.5 ± 9.7a 43.3 ± 9.0a 48.3 ± 8.6aq 48.7 ± 8.8a 50.6 ± 10.2a
  ISO 33.6 ± 5.4 56.0 ± 9.6a 52.1 ± 9.7a 47.1 ± 8.6a 8.9 ± 9.2a 51.3 ± 10.0a 52.3 ± 7.2a 51.5 ± 11.7a
PaO2 (mmHg) SEVO 67.70 ± 21.37 248.16 ± 177.47a 227.53 ± 181.16a 397.88 ± 166.10a 306.52 ± 172.38a 308.60 ± 107.28a 361.28 ± 137.38a 344.25 ± 126.63a
  ISO 72.89 ± 13.37 240,58 ± 191.60a 302.71 ± 173.45a 300.78 ± 137.90a 295.11 ± 139.80a 317.45 ± 131.76a 370.55 ± 164.92a 373.39 ± 114.11a
RT (°C) SEVO 39.02 ± 0.35 38.70 ± 0.46 38.42 ± 0.76 38.17 ± 0.94 37.80 ± 1.11 37.50 ± 1.23 37.28 ± 1.35 37.05 ± 1.45
  ISO 38.52 ± 0.68 39.20 ± 0.57 39.09 ± 0.59 38.74 ± 0.70 38.27 ± 0.88 38.00 ± 0.92 37.67 ± 0.95 37.45 ± 1.13
  1. Data are expressed as mean ± 1SD.
  2. B: basal values; I: induction values; 15, 30, 45, 60, 75, 90: stage of anaesthesia (expressed in minutes); HR: heart rate; RR: respiration rate; SpO 2 (%): arterial oxyhaemoglobin saturation;
  3. ETCO 2 (mmHg): end-tidal CO2; RT (°C): rectal temperature; ND: not done.
  4. Arterial blood gas values: PaCO2 (mmHg), PaO2(mmHg) and pH.
  5. aSignificantly different from baseline value (P < 0.05); bSignificantly different from ISO group (P < 0.05).