Table 1 Single nucleotide polymorphisms (SNPs) associated with individual groups in this study

Se4047

G

A

T

A

A

C

A

G

A

A

G

C

T

T

G

A

C

G

G

Group

Total isolates (Irish, UK)

A

11 (8, 3)

*

*

*

*

*

*

*

*

*

*

*

T

*

*

A

*

*

*

*

B

15 (15, 0)

*

*

*

*

*

*

*

*

G

*

*

T

*

*

A

G

*

*

*

C

41 (34, 7)

*

*

*

*

*

*

*

*

*

*

*

T

*

*

A

G

*

*

*

D

4 (4, 0)

*

*

*

*

T

*

G

A

*

*

*

*

*

C

A

G

*

A

*

E

6 (6, 0)

*

*

*

*

*

*

*

*

*

*

A

T

*

*

A

G

*

*

*

F

2 (0, 2)

*

*

*

*

G

G

*

*

*

*

*

*

*

*

A

*

*

*

*

G

57 (52, 5)

*

*

*

*

T

*

G

A

*

*

*

*

*

C

A

*

*

A

*

H

7 (6, 1)

*

*

*

*

G

*

G

*

*

G

*

*

*

C

A

*

*

A

*

I

2 (2, 0)

*

*

*

G

*

*

*

*

*

*

*

T

*

*

A

G

*

*

*

J

2 (1, 1)

*

*

*

*

*

*

G

*

*

*

*

*

*

C

A

*

*

A

*

K

4 (4, 0)

T

*

*

*

T

*

G

A

*

*

*

*

*

C

A

*

*

A

*

L

3 (3, 0)

*

G

*

*

T

*

G

A

*

*

*

*

*

C

A

*

*

A

*

M

2 (0, 2)

*

*

*

*

G

G

*

*

*

*

*

*

*

*

A

*

*

*

A

Single isolates

EI3

1 (1, 0)

*

*

*

*

T

*

G

A

*

*

*

*

*

C

A

*

T

A

*

EI4

1 (1, 0)

*

*

*

*

*

*

*

A

G

*

*

T

*

*

A

G

T

A

*

EI5

1 (1, 0)

T

*

*

*

*

*

*

*

*

*

*

T

*

*

A

G

*

*

*

EI8

1 (1, 0)

*

*

*

*

T

*

ATA^a

G

A

*

*

*

*

*

C

A

*

*

A

*

UK11

1 (0 , 1)

*

*

*

*

T

*

*

*

*

*

*

*

C

*

A

*

*

*

*

UK21

1 (0, 1)

*

*

A

*

T

*

G

A

*

*

*

*

*

C

A

G

*

A

*

Se4047 residue

Ser

Arg

Ser

Ser

Glu

Ala

Ser

Arg

Asp

Ala

Leu

Ser

Asn

Val

His

Pro

Ala

Val

SNP generated residue

Ile

Gly

Arg

Gly

Asp

Gly

Ile

Asn, Asp, Gly^b

Gly

Gly

Thr

Phe

Pro

n/c^c

Met

Arg

Leu

Thr

Ile