Figure 1
From: Erythrocyte pyruvate kinase deficiency in three West Highland white terriers in Ireland and the UK
Results of polyacrylamide gel electrophoresis of genomic DNA amplified by means of the polymerase chain reaction. N = genotypically normal. A = WHWT affected with PK deficiency. MW + Molecular weight markers, units are base pair (bp). 1 is the negative control, 2 is the positive control, 3 is a carrier (C), 4 is an affected WHWT and 5 is the affected WHWT from Ireland. Note the 6 bp larger band caused by the insertion mutation.