Table 3 Specific criteria for assessment of histopathology and scoring system
Parameter | Description | Score | Final overall score of histopathology |
|---|---|---|---|
Neutrophils | Not present | 0 | (0–12) |
Lymphocytes | 100–200 cells per 3 fields- mild | 1 | |
Plasma cells | 201–300 cells per 3 fields- moderate | 2 | |
Eosinophils | > 300 cells per 3fields- severe | 3 | |
Total inflammation score (0–12) | Mild (0–3) | 1 | 0–2 (−) absent 3–5 (+) mild 6–9 (++) moderate 9 (+++) severe |
Moderate (4–6) | 2 | ||
Severe > 7 | 3 | ||
Epithelial and goblet cell hyperplasia | Mild (focal thickened epithelium) | 1 | |
Moderate (multifocal thickened epithelium) | 2 | ||
Severe (diffuse thickened epithelium) | 3 | ||
Mucosal oedema | Mild (present in less than 20% of 3 random fields) | 1 | |
Moderate (20–40% of 3 random fields) | 2 | ||
Severe (> 40% of 3 random fields) | 3 |