Development of superficial lung lesions monitored on farm by serial ultrasonographic examination in sheep with lesions confirmed as ovine pulmonary adenocarcinoma at necropsy

Table 1 Results of ultrasonography and PME of sheep in group 1 (sheep pastured together and re-scanned at regular intervals)

Sheep	lung	Approx. depth of hyperechoic area (mm)						Post mortem results
ID		Weeks from first scan						visible	LF	BCS	OPA	Other
No.		0	6	9	11	13	16	OPA	(ml)	(0–5)	histo	path
1337	L	10	15	30	40	35	30	Early	0	3.5	Pos
	R	0	0	0	0	0	0
5381	L	0	0	3	0	3	10	Adv	4	3.5	Pos	pl
	R	20	30	30	30	40	40
18823	L	30	35	40	50	50	50	Mod	0	3	Pos
	R	0	0	0	0	0	0
15786	L	5	40	50	60	60	70	Adv	6	3	Pos	pl
	R	0	0	0	0	8	20
2806	L	15	20	20	30	25	40	Pos?	0	4	Pos
	R	10	0	10	10	10	20
4777	L	3	3	15	30	40		Adv	0	2	Pos
	R	3	50	50	60	60
15733	L	20	30	40	50	60		Adv	20	3	Pos	pl
	R	0	3	30	40	40
5466	L	15	25	50	40			Adv	40	2	Pos
	R	50	50	60	60
4709	L	20	40					Adv	10	3.5	Pos	pl
	R	2	40
2584	L	0	0					Mod	0	3	Pos	b
	R	2	30
4803	L	0	0	0	0	0	0	Neg?	0	3.5	Pos	b,p
	R	25	3	0	2	2	5
5182	L	0	0	0	0	0	0	Neg?	0	3.5	Pos	p
	R	10	20	0	0	0	0
6743	L	15	0	0	0	0	0	Neg	0	4	Neg	p
6750	L	2	0	0	0	3	0	Neg?	0	3	Pos
11641	L	15	0	0	0	0	0	Neg?	0	3	Neg	p
16610	L	3	5	25				Neg	ND	0.5	Neg	b
	R	30	60	60

The approximate depth of the hypoechoic area was determined from videos of the sonograms. Visible lesions indicative of OPA at PME were classified as follows: affecting > 40% of the lung (Adv), affecting 10–40% of the lung (Mod), affecting < 10% of the lung (Early), > 3 consolidated lesions (Pos?), 1–3 discrete consolidated lesions < 1 cm (Neg?), No visible lesions (Neg). LF: Volume of lung fluid collected by tipping after euthanasia. BCS: body condition score (scale 1–5). OPA histo: histological confirmation of OPA status. Other path: signs of bacterial (b) or parasitic (p) pathologies by gross PME and/or histopathology, pleurisy (pl)

ISSN: 2046-0481