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Table 1 Pharmacokinetic parameters of tamoxifen after single oral administration (0.25 mg/kg) in six adult healthy horses

From: Tamoxifen in horses: pharmacokinetics and safety study

  Animal Mean SD
1 2 3 4 5 6
AUC 0-∞ (pg-mL/min) 5172.6 4069.4 4689.7 8974.0 4775.2 4624.9 5384.3 1793.9
Cmax (pg/mL) 5.7 3.3 5.5 9.6 7.4 5 6.1 2.2
Tmax (h) 1 4 4 6 2 1 3.0 2.0
t1/2E (h) 10.24 13.53 14.35 5.35 7.13 12.5 10.5 3.6