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Table 5 Leukogram values before (Control) and after 4 (S1), 8 (S2), 11 (S3), and 15 (S4) days of treatment with tamoxifen (0.25 mg/kg, PO q 24 h for 7 days) in healthy adult horses (n = 20)

From: Tamoxifen in horses: pharmacokinetics and safety study

Sample Control S1 S2 S3 S4 Reference Range
Parameter Mean ± SD
Leukocytes 9443 ± 2595 9360 ± 2201 9310 ± 1958 8990 ± 1539 9225 ± 1761 7200–14,400 cel/μL
Basophils 46 ± 63.1 29 ± 71.85 26 ± 40.27 39 ± 50.92 54 ± 65.98 0–300 cel/μL
Eosinophils 467 ± 315.22 347 ± 275.49 406 ± 269.58 370 ± 328.23 259 ± 214.02 100–800 cel/μL
Neutrophils 4923 ± 1226 5232 ± 1341 5164 ± 1208 4862 ± 948.43 5108 ± 1388 2200–6100 cel/μL
Band neutrophils 0 ± 0 4 ± 16.77 0 ± 0 5 ± 21.24 0 ± 0 0–200 cel/μL
Juvenile neutrophils 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 cel/μL
Lymphocytes 3395 ± 1169 3433 ± 1343 3406 ± 1455 3482 ± 1042 3475 ± 1455 1500–6500 cel/μL
Monocytes 202 ± 94.16 215 ± 116.37 151 ± 112.77 232 ± 159.13 211 ± 159.32 0–600 cel/μL