Skip to main content

Table 1 Reported pathological findings associated with natural congenital Schmallenberg virus infection in domestic ruminants (bovine, ovine and caprine)

From: Schmallenberg virus: a systematic international literature review (2011-2019) from an Irish perspective

Species Gross pathology Histopathology References
Bovine Head and CNS Non-suppurative meningo-encephalitis, [108, 109, 111, 112]
Porencephaly, hydranencephaly, brain stem hypoplasia, cerebellar hypoplasia, cerebellar dysplasia, micromyelia
Non-suppurative poliomyelitis, skeletal muscle hypoplasia, lymphoid depletion in thymus and lymph node, chronic hepatitis
Skeletal
Arthrogryposis, torticollis, lordosis, scoliosis, kyphosis, cranial malformations, brachygnathism inferior, prognathia
Visceral
Ectopia cordis, pulmonary hypoplasia, ventricular septal defect
Ovine Head and CNS Non-suppurative meningo-encephalitis, skeletal muscle hypoplasia, lymphoid depletion in spleen or lymph node, cataract, haematopoietic cellularity in bone marrow [4, 6, 109]
Brachynathism inferior, domed skull, flattened skull, hydranencephaly, hydrocephalus, micrenencephaly, macrocephaly, brainstem hypoplasia, cerebral hypoplasia, cerebellar hypoplasia, cerebellar dysplasia, micromyelia
Skeletal
Arthrogryposis, torticollis, lordosis, scoliosis, kyphosis,
Visceral
Cardiac ventricular septal defect, unilateral hydronephrosis, colonic atresia
Caprine Head and CNS Non-suppurative meningo-encephalitis, nonsuppurative poliomyelitis [4, 113]
Hydrocephalus, porencephaly, cerebellar hypoplasia
Skeletal
Arthrogryposis, vertebral deformities, brachynathism inferior
Visceral
Pulmonary hypoplasia,
  1. This table is adapted from Doceul et al. (2017) [114]