Group | 0 | 1 | 2 | 5 | 10 | 14 | |
---|---|---|---|---|---|---|---|
AST (U/l) | control | 58.83 ± 2.8 | 59 ± 2.42 | 56.67 ± 2.38 | 56.17 ± 2.4 | 56.33 ± 2.51 | 55 ± 3.28 |
0.5 mg/kg | 60.17 ± 3.75 | 51 ± 7.13 | 56 ± 4.5 | 57.83 ± 0.4 | 56.17 ± 1.54 | 55.5 ± 2.58 | |
1 mg/kg | 61.83 ± 3.83 | 57.5 ± 0.5 | 54.17 ± 2.46 | 60.5 ± 0.99 | 62.5 ± 4.72 | 55.17 ± 2.83 | |
LDH (U/l) | control | 1159.83 ± 66.26 | 1217.33 ± 90.77 | 1148.5 ± 58.26 | 1140 ± 75.18 | 1165.17 ± 71.55 | 1117.33 ± 75.07 |
0.5 mg/kg | 1154.83 ± 95.05 | 1108.67 ± 93.88 | 1110.5 ± 107.98 | 1017.83 ± 85.1 | 1048.5 ± 71.01 | 1168.33 ± 97.59 | |
1 mg/kg | 1180.67 ± 24.07 | 1226.67 ± 34.88 | 1157.67 ± 34.42 | 1093 ± 65.04 | 1179.5 ± 132.76 | 1291.33 ± 76.73 | |
CK (U/l) | Control | 88.43 ± 11.96 | 94.27 ± 9.57 | 113.65 ± 16.11 | 100.42 ± 8.41 | 143.48 ± 10.7 | 122.33 ± 11.37 |
0.5 mg/kg | 107.12 ± 29.22 | 182.13 ± 86.75 | 131.73 ± 25.42 | 100.2 ± 9.7 | 184.9 ± 34.76 | 149.78 ± 12.96 | |
1 mg/kg | 103.28 ± 17.96 | 79.33 ± 13.38 | 98.77 ± 24.75 | 99.82 ± 14.27 | 127.03 ± 6.45 | 169.37 ± 22.36 | |
TG (mmol/l) | control | 0.18 ± 0.03 | 0.25 ± 0.03 | 0.24 ± 0.03 | 0.23 ± 0.03 | 0.15 ± 0.01 | 0.22 ± 0.02 |
0.5 mg/kg | 0.16 ± 0.02 | 0.19 ± 0.02 | 0.24 ± 0.03 | 0.18 ± 0.04 | 0.2 ± 0.03 | 0.2 ± 0.03 | |
1 mg/kg | 0.42 ± 0.28 | 0.2 ± 0.04 | 0.26 ± 0.04 | 0.24 ± 0.02 | 0.16 ± 0.02 | 0.23 ± 0.04 | |
Chol (mmol/l) | control | 1.66 ± 0.15 | 1.9 ± 0.09 | 1.76 ± 0.06 | 1.42 ± 0.1 | 2.12 ± 0.11 A | 2 ± 0.17 |
0.5 mg/kg | 1.9 ± 0.2 | 1.88 ± 0.17 | 1.83 ± 0.1 | 1.55 ± 0.13 | 1.67 ± 0.17B | 1.97 ± 0.27 | |
1 mg/kg | 1.54 ± 0.09 | 1.55 ± 0.15 | 1.71 ± 0.17 | 1.78 ± 0.12 | 1.78 ± 0.12AB | 1.72 ± 0.23 | |
Gluc (mmol/l) | control | 6.21 ± 0.24 | 6.3 ± 0.35 | 5.91 ± 0.29 | 6.07 ± 0.33 | 5.96 ± 0.29 | 5.72 ± 0.29 |
0.5 mg/kg | 5.79 ± 0.41 | 6.55 ± 0.46 | 5.73 ± 0.06 | 5.68 ± 0.29 | 5.26 ± 0.3 | 5.39 ± 0.22 | |
1 mg/kg | 6.79 ± 0.25 | 6.93 ± 0.52 | 6.64 ± 0.3 | 6.26 ± 0.32 | 5.28 ± 0.41 | 5.58 ± 0.35 | |
ALB (g/l) | control | 32.87 ± 0.93 | 33.5 ± 0.82 | 34.55 ± 0.98 | 34.73 ± 1.41 | 33.8 ± 0.74 | 34.57 ± 0.96 |
0.5 mg/kg | 31.63 ± 0.63 | 31.02 ± 0.63 | 32.03 ± 0.96 | 32.13 ± 1.09 | 32.35 ± 0.61 | 33.02 ± 0.7 | |
1 mg/kg | 32.55 ± 1.16 | 33.45 ± 0.66 | 33.47 ± 0.51 | 33.83 ± 1.01 | 33.72 ± 0.96 | 35.33 ± 0.67 | |
TP (g/l) | control | 55.73 ± 1.91 | 48.1 ± 8.5 | 56.95 ± 1.47 | 55.75 ± 1.96 | 53.28 ± 2.34 | 51.9 ± 1.66 |
0.5 mg/kg | 56.05 ± 1.22 | 53.07 ± 1.43 | 55.05 ± 2.22 | 51.23 ± 2.17 | 48.63 ± 1.08 | 49.22 ± 1.71 | |
1 mg/kg | 56.77 ± 2.32 | 55.02 ± 1.73 | 55.12 ± 1.65 | 56.8 ± 1.85 | 51.52 ± 2.07 | 51.68 ± 2.01 | |
Urea (mmol/l) | control | 4.28 ± 0.47 | 4.15 ± 0.46AB | 4.26 ± 0.45 | 4.51 ± 0.18 | 4.52 ± 0.36 | 4.51 ± 0.34 |
0.5 mg/kg | 3.98 ± 0.37 | 3.95 ± 0.21 A | 4.25 ± 0.25 | 4.87 ± 0.34 | 4.6 ± 0.46 | 3.79 ± 0.51 | |
1 mg/kg | 4.8 ± 0.48 | 4.58 ± 0.58B | 4.71 ± 0.28 | 6.8 ± 1.87 | 5.27 ± 0.25 | 4.27 ± 0.43 | |
Crea (µmol/l) | control | 83.32 ± 4.12AB | 89.9 ± 4.08 | 90.28 ± 8.14 | 91.08 ± 5.85 | 93.58 ± 8.02 | 94.85 ± 11.69 |
0.5 mg/kg | 77.52 ± 2.61 A | 80.5 ± 3.18 | 84.5 ± 5.43 | 87.05 ± 5.03 | 84.9 ± 4.29 | 90.52 ± 6.15 | |
1 mg/kg | 90.68 ± 3.3B | 92.13 ± 1.87 | 96.42 ± 3.45 | 133.62 ± 29.65 | 100.6 ± 4.53 | 92.5 ± 3.35 |