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Table 1 Performance of various tests in identifying failure of passive transfer, compared to radial immunodiffusion as a reference method, at the cut-off points recommended in the literature. The uniformly high sensitivity, and the widely varying specificity, may be noted. Positive and negative predictive values have been calculated based on the reported prevalence of FPT in Irish calves [14]

From: Comparison of rapid laboratory tests for failure of passive transfer in the bovine

Test

Recommended cut-off point

Sensitivity(95 % CI)

Specificity (95 % CI)

% of animals classified correctly

Positive predictive value

Negative predictive value

GGT

100 IU/L [29]

0.9726 (0.9045-0.9967)

0.9811 (0.8993-0.9995)

98 %

0.9901

0.9486

ELISA

10 mg/ml [39]

0.9726 (0.9045-0.9967)

0.9811 (0.8993-0.9995)

98 %

0.9901

0.9486

Globulin

20 mg/ml [15]

1.0000 (0.9507-1.0000)

0.8491 (0.7241-0.9325)

94 %

0.9279

1.0000

STP

52 mg/ml [38]

1.0000 (0.9507-1.0000)

0.5660 (0.4228-0.7016)

82 %

0.8173

1.0000

ZST

20 units [20]

0.9863 (0.9260-0.9997)

0.3019 (0.1834-0.4434)

70 %

0.7328

0.9190