Table 1 Primary outcome: global ocular clinical score. Each clinical sign (conjunctivitis, ocular discharge, eye irritation, corneal opacity/pigmentation/ vessels) is rated from 0 to 3. The global ocular clinical score corresponds to the sum of these individual scores. (Adapted from Williams et al. [2] and Da Silva et al. [4])
Ocular clinical sign | Score |
|---|---|
Conjunctivitis | 0 = None 1 = Mild hyperaemia 2 = Moderate to severe hyperaemia 3 = Moderate to severe hyperaemia with chemosis |
Ocular discharge | 0 = None 1 = Mild ocular discharge 2 = Moderate mucoid ocular discharge 3 = Severe mucoid ocular discharge |
Eye irritation (frequency of eye blinking and palpebral opening) | 0 = None 1 = Some eye blinking 2 = Frequent eye blinking and narrow palpebral opening 3 = Eye is mainly closed |
Corneal opacity, pigmentation, and vessels | 0 = None 1 = < 25% of the surface 2 = 25% to 50% of the surface 3 = > 50% of the surface |