Table 1 Recommended treatments for exotic arthropod-borne diseases of dogs and cats
From: Exotic diseases of dogs and cats at risk of importation to Ireland
Disease | Generic product | Recommended dose rates | Interval and duration of therapy | Notes/toxicity |
|---|---|---|---|---|
LEISHMANIOSIS | Allopurinol (purine analogue) Meglumine antimonate (pentavalent antimonial) | Dogs: 10-15 mg/kg PO Dogs: 100 mg/kg SC | q12-24 h q24-48 h for 20-40 days | Increase uric acid levels Pain, swelling at injection site, renal dysfunction, increased liver enzymes. |
BABESIOSIS | Â | Â | Â | Â |
B. canis canis | Imidocarb dipropionate | 5.0-6.6 mg/kg IM or SC | Once, then repeat 2-3 weeks | Uncommon salivation, lacrimation, diarrhoea, vomiting, muscle tremor, pain on injection. |
B. gibsoni | Ataquavone in combination with azithromycin | 13.3 mg/kg PO + 10 mg/kg PO | q8 hrs + q24 hrs for 10 days | Â |
B. felis | Primiquine phosphate | 0.3 mg/kg PO | q24 hrs for 14 days | Â |
EHRLICHIOSIS | Â | Â | Â | Â |
| Â | Doxycycline | Dogs: 5-10 mg/kg PO Cats: 5 mg/kg PO | q12-24 h for 14-21 days | Stain teeth in first month of life and in last trimester pregnancy. Anorexia especially in cats, vomiting, diarrhoea. |
ANAPLASMOSIS | Â | Â | Â | Â |
| Â | Oxytetracycline | Dogs and cats 7-11 mg/kg IM, SC Dogs 25 mg/kg PO | q8 h for 14-21 days q8 h for 14-21 days | Â |
DIROFILARIOSIS | Â | Â | Â | Â |
| Â | Melarsomine | Protocol A 2.2 mg/kg IM or Protoocol B 2.5 mg/kg IM | Once then again at 3 h Once then repeat at 24 h | Dosing protocol dependant on clinical classification. Subclinical disease: Protocols A or B Moderate disease: Protocol B Severe: Single2.5 mg/kg treatment followed by Protocol B 1-2 months later. |