Table 1 Clinical findings, gross pathology and histopathological examination of studied dogs
From: Myocarditis in dogs: etiology, clinical and histopathological features (11 cases: 2007–2013)
Dog no. | Breed age sex | Clinical findings | Reason of death | Gross pathology | Histopathology and IHC |
|---|---|---|---|---|---|
1. | Miniature Schnauzer 3 y M | AF; signs of dilated cardiomyopathy; nephritis | Euthanasia due to heart failure | Generalized heart chamber dilation; ascites, hydrothorax, hydropericardium, enlargement of liver and spleen | Lympho-plasmocytic inflammation (+ to ++); cardiomyocyte degeneration (++ to +++); fibrosis (+ to ++); IHC: B. burgdorferi (+) |
2. | German Shepherd 8 y M | AF; signs of dilated cardiomyopathy; recurrent lameness | Euthanasia due to heart failure | Generalized heart chamber dilation; thickening of pericardial sack; ascites, hydrothorax, hydropericardium, enlargement of liver and spleen | Lympho-plasmocytic inflammation (+ to ++); cardiomyocyte degeneration (+ to ++); fibrosis (+ to ++); IHC: B. burgdorferi (+) |
3. | Siberian Husky 6 y F | VPCs; mass of unknown aetiology in LV | Sudden cardiac death | embolic material in aorta and LV | Granulocytic inflammation (+++); lympho-plasmocytic inflammation (+); cardiomyocyte degeneration (+++); IHC: B. burgdorferi (+) |
4. | Mongrel 5 y F | no rhythm disturbances; signs of dilated cardiomyopathy | Euthanasia due to heart failure | Generalized heart chamber dilation; ascites, hydrothorax, hydropericardium, enlargement of liver and spleen | Lympho-plasmocytic inflammation (+); cardiomyocyte degeneration (+ to ++); fibrosis (+); IHC: B. burgdorferi (+) |
5. | Mongrel 7 y M | no rhythm disturbances; signs of dilated cardiomyopathy | Euthanasia due to heart failure | Generalized heart chamber dilation; ascites, hydrothorax, hydropericardium, enlargement of liver and spleen | Lympho-plasmocytic inflammation (+ to ++); cardiomyocyte degeneration (+); fibrosis (+ to ++); IHC: B. burgdorferi (+) |
6. | Mongrel 3 y F | no rhythm disturbances; signs of dilated cardiomyopathy | Euthanasia due to heart failure | Generalized heart chamber dilation; ascites, hydrothorax, hydropericardium, enlargement of liver and spleen | Lympho-plasmocytic inflammation (+); cardiomyocyte degeneration (+); fibrosis (+); IHC: B. burgdorferi (+) |
7. | Mongrel 13 y M | VT with idioventricular rhythm; LVW hypertrophy and MR; dyspnoea | Euthanasia due to non-cardiac tumour | Hypertrophy of LVW and MV degeneration | Lympho-plasmocytic inflammation (+); cardiomyocyte degeneration (+); |
8. | Cane Corso 3 y M | AF with rapid ventricular response; signs of dilated cardiomyopathy | Sudden cardiac death | Generalized heart chamber dilation | Lympho-plasmocytic inflammation (+ to ++); cardiomyocyte degeneration (++ to +++); fibrosis (+) |
9. | Great Dane 2.5 y M | AF with rapid ventricular response; signs of dilated cardiomyopathy | Sudden cardiac death | Generalized heart chamber dilation | Lympho-plasmocytic inflammation (+ to +++); cardiomyocyte degeneration (+ to ++); fibrosis (+) |
10. | Mongrel 4 y F | VT; LV dilatation; dyspnoea | Sudden cardiac death | Infarct of the LVW | Lympho-plasmocytic inflammation (+ to ++); granulocytic inflammation (+ to +++); cardiomyocyte degeneration (++ to +++) |
11. | Boxer 7 y M | VT; no heart enlargement; neurological symptoms | Euthanasia due to neurological symptoms | No visible signs of heart failure | Lympho-plasmocytic inflammation (+ to ++); cardiomyocyte degeneration (+); fibrosis (+); lymphocytic inflammation of brain (+++) |