Table 4 Criteria used for the classification of lungs based on histologic examination
Histological lesion category | Description |
|---|---|
Abscess | Thick fibrous capsule (or part thereof) surrounding viable +/− degenerate neutrophils +/− central liquefactive necrosis |
Bronchopneumonia | Alveolar and bronchial/bronchiolar lumina filled with admixed neutrophils, macrophages and lymphocytes, +/− type 2 pneumocyte hyperplasia, bronchiolitis obliterans, oedema, bacterial colonies, regions of fibrosis |
Interstitial thickening | Extensive-diffuse, mild-marked thickening of the alveolar septa due to smooth muscle hypertrophy +/− fibroblasts. |
Histologically Suspect OPA (HSO) | Single-multifocal, well-demarcated-infiltrative tumours with papillary/lepidic/acinar growth patterns consisting of cuboidal-columnar cells supported by a fine fibrous stroma and surrounded by macrophage infiltration. |
Parasitic infestation | One or more of the following: nematode eggs/larvae, eosinophilic granulomas, eosinophil-rich interstitial and intra-alveolar infiltrates. |
Other | Pathological changes not falling into any of the other categories described. |
Normal | No pathological changes |