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Table 4 Erythrogram values before (Control) and after 4 (S1), 8 (S2), 11 (S3), and 15 (S4) days of treatment with tamoxifen (0.25 mg/kg, PO q 24 h for 7 days) in healthy adult horses (n = 20)

From: Tamoxifen in horses: pharmacokinetics and safety study

Sample Control S1 S2 S3 S4 Reference Range
Parameter Mean ± SD
Erythrocyte 7.71 ± 1.21 7.44 ± 1.03 7.49 ± 1.03 7.42 ± 0.94 7.32 ± 0.97 4.9–8.5 × 10^6 μL
Hematocrit 36 ± 0.05 36 ± 0.05 36 ± 0.05 36 ± 0.05 35 ± 0.04 27–42%
Hemoglobin 123 ± 19.53 120 ± 15.41 121 ± 16.48 119 ± 14.45 117 ± 14.15 94–147 g/L
MCV 45 ± 10.42 47 ± 2.15 48 ± 2.27 46 ± 11.80 47 ± 2.15 42–62 fL
MCHC 338 ± 21.12 339 ± 13.60 341 ± 25.55 316 ± 80.45 340 ± 12.60 320–380 g/L
Immature Eryth. 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0%
Platelets 152 ± 41.2 163 ± 48.8 159 ± 45.4 150 ± 46.8 153 ± 55.3 90-210 × 103/ μL
Proteins 71 ± 4.03 72 ± 6.64 74 ± 5.76 72 ± 4.77 74 ± 3.85 68–84 g/L
Fibrinogen 3 ± 1.10 3 ± 2.90 3 ± 2.18 3 ± 0.81 3 ± 2.06 < 5 g/L