Group | N | 0 | 1 | 2 | 5 | 10 | 14 | |
---|---|---|---|---|---|---|---|---|
WBC (109/L) | control | 6 | 6.38 ± 0.51 | 7.11 ± 0.54 | 7.05 ± 0.65 | 6.35 ± 0.82 | 7.19 ± 0.43 | 6.13 ± 0.35 |
0.5 mg/kg | 6 | 6.38 ± 0.85 | 6.42 ± 0.97 | 6.07 ± 0.99 | 7.85 ± 0.73 | 6.85 ± 0.63 | 6.84 ± 0.74 | |
1 mg/kg | 6 | 6.55 ± 0.43 | 6.8 ± 0.92 | 6.53 ± 0.8 | 7.03 ± 0.88 | 7.31 ± 0.54 | 6.76 ± 0.64 | |
RBC (10¹²/L) | control | 6 | 7.63 ± 0.6 | 7.47 ± 0.5 | 7.35 ± 0.63 | 7.61 ± 0.45 | 7.01 ± 0.39 | 6.99 ± 0.58 |
0.5 mg/kg | 6 | 7.23 ± 0.47 | 7.02 ± 0.32 | 7.68 ± 0.69 | 7.69 ± 0.69 | 7.57 ± 0.6 | 7.61 ± 0.54 | |
1 mg/kg | 6 | 7.81 ± 0.5 | 7.39 ± 0.41 | 7.6 ± 0.32 | 8.46 ± 0.63 | 8 ± 0.43 | 8.02 ± 0.51 | |
HGB (g/dL) | Control | 6 | 8.73 ± 0.61 | 8.95 ± 0.97 | 9.07 ± 0.95 | 7.57 ± 1 | 8.67 ± 0.86 | 8.97 ± 0.87 |
0.5 mg/kg | 6 | 7.72 ± 0.75 | 7.65 ± 0.77 | 8.12 ± 1.06 | 7.85 ± 1.02 | 7.25 ± 0.9 | 7.43 ± 0.97 | |
1 mg/kg | 6 | 8.93 ± 0.71 | 8.33 ± 0.6 | 8.5 ± 0.51 | 9.45 ± 0.91 | 8.6 ± 0.67 | 8.55 ± 0.88 | |
HCT (L/L) | control | 6 | 32.08 ± 1.75 | 31.37 ± 1.04 | 31.2 ± 0.83 | 31.62 ± 0.95 | 32.43 ± 1.56 | 32.52 ± 1.85 |
0.5 mg/kg | 6 | 28.62 ± 2.47 | 27.73 ± 1.93 | 30.23 ± 3.55 | 29.72 ± 3.48 | 27.45 ± 3.24 | 27.2 ± 3.32 | |
1 mg/kg | 6 | 32.67 ± 2.51 | 30.7 ± 2.19 | 31.28 ± 1.83 | 35.83 ± 3.65 | 32.13 ± 2.39 | 30.37 ± 2.64 | |
MCV (fL) | Control** | 6 | 38.9 ± 1.19 | 37.17 ± 1.1 | 35.37 ± 1.35 | 36.87 ± 1.1 | 35.13 ± 1.14 | 34.02 ± 1.29 |
0.5 mg/kg* | 6 | 39.33 ± 1.33 | 39.35 ± 1.34 | 39.98 ± 1.38 | 37.22 ± 1.34 | 36 ± 1.65 | 35.08 ± 1.89 | |
1 mg/kg** | 6 | 40.73 ± 1.01 | 40.38 ± 0.95 | 40.05 ± 0.9 | 39 ± 1.22 | 39.72 ± 0.87 | 37.63 ± 1.15 | |
MCH (pg) | control | 6 | 12.07 ± 0.68 | 11.73 ± 0.65 | 11.65 ± 0.67 | 11.58 ± 0.52 | 11.38 ± 0.44 | 11 ± 0.47 A |
0.5 mg/kg | 6 | 10.57 ± 0.43 | 10.77 ± 0.68 | 10.42 ± 0.51 | 10.05 ± 0.48 | 10.57 ± 0.5 | 9.55 ± 0.61B | |
1 mg/kg | 6 | 11.38 ± 0.36 | 11.22 ± 0.34 | 11.12 ± 0.31 | 11.1 ± 0.31 | 11.23 ± 0.28 | 10.57 ± 0.55AB | |
MCHC (g/dL) | control | 6 | 27.18 ± 0.29 | 27.93 ± 0.69 | 27.45 ± 0.45 | 27.25 ± 0.58 | 27.05 ± 0.38 | 26.97 ± 0.7 |
0.5 mg/kg | 6 | 26.88 ± 0.29 | 27.27 ± 0.94 | 26.65 ± 0.42 | 26.22 ± 0.39 | 26.7 ± 0.29 | 27.13 ± 0.49 | |
1 mg/kg | 6 | 27.32 ± 0.41 | 27.1 ± 0.41 | 27.08 ± 0.34 | 26.42 ± 0.24 | 26.97 ± 0.23 | 28 ± 0.69 | |
PLT (109/L) | Control* | 6 | 533.17 ± 69.4 | 653 ± 74.43 | 840.83 ± 42.06 | 826.83 ± 68.33 | 851.5 ± 50.76 | 737.17 ± 34.63 |
0.5 mg/kg* | 6 | 537.17 ± 51.05 | 672.83 ± 45.89 | 888.17 ± 40.02 | 775 ± 100.1 | 718 ± 86.31 | 685.67 ± 77.2 | |
1 mg/kg* | 6 | 464.5 ± 51.75 | 595.33 ± 71.16 | 744.5 ± 81.31 | 707.67 ± 93.61 | 790 ± 63.31 | 692.17 ± 68.17 |