Table 3 Comparison of echocardiographic measurements among the three groups
Variable | Dogs without MMVD (Group 0, n = 13) | Normotensive dogs with MMVD stage B (Group 1, n = 30) | Systemic hypertensive dogs with MMVD stage B (Group 2,n = 7) | p–value (Kruskal–Wallis test) |
|---|---|---|---|---|
Echo | ||||
LA/AO | ||||
Median (IQR) | 1.47(1.25–1.51) | 2.00 (1.87–2.26) | 2.07 (1.81–2.34) | |
p–value (Dunn’s test) | Group 0 vs. Group 1: < 0.001* | < 0.001† | ||
Group 0 vs. Group 2: 0.004* | ||||
Group 1 vs. Group 2: 1 | ||||
E peak(m/s) | ||||
Median (IQR) | 0.7(0.6–0.795) | 1.21 (1.07–1.29) | 1.15 (1.06–1.45) | |
p–value (Dunn’s test) | Group 0 vs. Group 1: 0.001* | 0.001† | ||
Group 0 vs. Group 2: 0.016* | ||||
Group 1 vs. Group 2: 1 | ||||
MR(m/s) | ||||
Median (IQR) | ND | 5.53 (5.17–5.95) | 6.11 (6.07–6.24) | |
p–value (Mann–Whitney U tests) | Group 1 vs. Group 2: 0.006^ | – | ||
LVIDDN | ||||
Median (IQR) | 1.3(1.24–1.345) | 1.67 (1.63–1.90) | 1.72 (1.57–1.77) | |
p–value (Dunn’s test) | Group 0 vs. Group 1: < 0.001* | 0.001† | ||
Group 0 vs. Group 2: 0.016* | ||||
Group 1 vs. Group 2: 1 | ||||
LVPWd/BW^0.232 | ||||
Median (IQR) | 0.41(0.3–0.43) | 0.43(0.38–0.50) | 0.44(0.41–0.45) | 0.430 |
VHS Median (IQR) | 9.6(9.5–9.95) | 10.60(10.03–10.80) | 10.4(9.85–11.10) | |
p–value (Dunn’s test) | Group 0 vs. Group 1: 0.041* | 0.048† | ||
Group 0 vs. Group 2: 0.272 | ||||
Group 1 vs. Group 2: 1 | ||||