Table 1 FDA-approved antimicrobials for use in dairy cattle to treat mastitis (adapted from NMPF, 2020)
Route of Administration | Antimicrobial class | Antimicrobial agents | Product name | Manufacturer |
|---|---|---|---|---|
Intramammary | Beta (β)-lactam Lincosamide | Penicillin G Amoxicillin Ceftiofur Cephapirin Cloxacillin Hetacillin Pirlimycin | Hanford’s/US Vet MASTICLEAR® Amoxi-Mast® SPECTRAMAST™ LC Today® Dariclox® Hetacin®K Pirsue® Sterile Solution | G.C. Hanford Mfg. Co Merck Animal Health Zoetis, Inc Boehringer Ingelheim Vetmedica, Inc Merck Animal Health Boehringer Ingelheim Vetmedica Zoetis, Inc |
Injectable | β-lactam Tetracyclines Sulphonamide | Ampicillin Ceftiofur Ceftiofur Ceftiofur Penicillin GOxytetracycline Sulfadimethoxine | Polyflex® EXCEDE® EXCENEL® RTU EZ Naxcel® Sterile Powder Agricillin® Agrimycin 200 Di-Methox Injection 40% | Boehringer Ingelheim Vetmedica, Inc Zoetis, Inc Zoetis, Inc Zoetis, Inc Agri Laboratories, Ltd Agri Laboratories, Ltd Agri Laboratories, Ltd |
Oral | Sulphonamide | Sulfadimethoxine | ALBON® Bolus | Zoetis, Inc |
Topical | Tetracyclines Polymyxins | Oxytetracycline Polymyxin B | Terramycin® Ophthalmic Ointment with Polymyxin | Zoetis, Inc |